Vision changes can sneak up on you — but what if the culprit isn't aging, genetics, or screen time… but the medications you're taking? Recent findings have raised red flags about certain prescription drugs being linked to macular degeneration, a serious eye condition that can lead to permanent vision loss.
If you or a loved one take medications like Izervay, Rexulti, or Austedo, this is something you should absolutely be aware of.
What Is Macular Degeneration?
Macular degeneration affects the central part of the retina, called the macula, which is responsible for sharp, straight-ahead vision. When it deteriorates, your ability to read, recognize faces, or drive can gradually — or suddenly — decline.
There are two main types:
Dry macular degeneration (most common and progresses slowly)
Wet macular degeneration (less common but more aggressive)
While age and genetics are major risk factors, new research suggests that certain medications may accelerate or contribute to macular damage.
Medications Potentially Linked to Macular Degeneration
Some drugs have drawn attention due to reported vision changes in users. Here are three being closely watched:
Izervay: This injectable drug is designed to treat geographic atrophy (an advanced form of dry AMD), but its long-term effects are still under review. Some concerns have been raised about inflammation and worsening eye conditions post-injection.
Rexulti: Used for depression and schizophrenia, Rexulti may affect the vascular system, which could potentially impact eye health over time.
Austedo: Prescribed for movement disorders, Austedo has been associated with various neurological side effects, and though rare, visual symptoms have been reported in some cases.
While these medications can be helpful for the conditions they treat, it’s essential to weigh the benefits against any potential risks — especially if you're already at risk for macular degeneration.
Signs You Shouldn’t Ignore
If you take any of the above medications and experience symptoms like:
Blurry or distorted central vision
Dark or empty spots in your field of vision
Increased difficulty with reading or seeing fine details
...you should speak to your eye doctor as soon as possible.
What You Can Do
Get regular eye exams — especially if you’re over 50 or on long-term medication.
Use protective eye drops if experiencing dry eyes, which can sometimes worsen macular issues.
Talk to your doctor about alternatives or adjustments to your medication if vision changes begin.
Ask about supplements like lutein and zeaxanthin, which may help support macular health.