Multiple myeloma is a rare yet serious form of blood cancer that develops in plasma cells—a type of white blood cell found in bone marrow.
What Is Multiple Myeloma?
While its name might not be familiar to many, the signs can be surprisingly subtle at first. Recognizing these early symptoms may help patients seek timely treatment and improve outcomes.
What Is Multiple Myeloma?
Plasma cells play a critical role in your immune system by producing antibodies to help fight infections. In multiple myeloma, abnormal plasma cells grow uncontrollably, crowding out healthy cells and affecting bone structure, kidney function, and immune response.
This condition mostly affects adults over 60, though it can appear earlier. It's slightly more common in men and African American populations. While the exact cause remains unclear, risk factors include a family history of the disease and exposure to certain chemicals.
Early Symptoms Often Overlooked
Many early signs of multiple myeloma can be mistaken for less serious issues. Here are symptoms to watch:
Bone pain, particularly in the back or ribs
Fatigue or feeling unusually weak
Frequent infections, due to impaired immune response
Unexplained weight loss
Excessive thirst or urination (can signal kidney issues)
Numbness or tingling, especially in the legs
If you’ve experienced any of these for an extended period, it’s worth discussing with a healthcare provider. They may order blood tests, imaging, or a bone marrow biopsy to investigate further.
How It’s Diagnosed and Treated
Diagnosis typically involves:
Blood and urine tests to detect abnormal proteins
Bone marrow biopsy to check for cancerous plasma cells
Imaging like MRIs or CT scans to detect bone damage
Treatment depends on the stage and severity. Common strategies include:
Targeted therapies that attack specific cancer cells
Chemotherapy
Stem cell transplants
Supportive treatments to protect bones and kidneys
While multiple myeloma is generally not considered curable, it is often manageable with modern treatment. Many patients live meaningful lives with ongoing care.
The Power of Early Detection
Like many cancers, the earlier multiple myeloma is identified, the better the treatment outcomes. But because its symptoms mimic other common issues, it’s often diagnosed late. Staying informed and acting on persistent health changes can make all the difference.