Amyloidosis is one of those conditions you rarely hear about—until it’s too late. Often mistaken for other health issues, it is important to spot the early signs before it's too late.

7 Silent Signs of Amyloidosis You Shouldn’t Ignore

🔍 1. Fatigue That Doesn’t Go Away

Sure, everyone gets tired. But if your fatigue is deep, persistent, and feels different than normal exhaustion, it might be worth a closer look.

🔍 2. Swelling in the Legs or Ankles

This isn’t your typical post-walk puffiness. It’s a slow-building fluid retention that can signal kidney or heart involvement.

🔍 3. Shortness of Breath

If stairs or simple tasks leave you gasping—despite no known lung issues—amyloid buildup in the heart could be interfering with circulation.

🔍 4. Numbness or Tingling in Hands/Feet

Often brushed off as carpal tunnel or “just getting older,” this could be a red flag of nerve involvement—common in amyloidosis cases.

🔍 5. Unexplained Weight Loss

When pounds drop off without trying—and you’re not dieting—it’s worth asking why. Metabolic disruption is a classic early clue.

🔍 6. Skin Changes or Easy Bruising

Thin, fragile skin or bruises appearing without injury? These may point to underlying vessel involvement.

🔍 7. Irregular Heartbeat or Chest Discomfort

Amyloidosis can impact heart rhythm—leading to symptoms easily confused with more common conditions.