In 2025, medical researchers are taking a closer look at prescription medications that may raise the risk of prostate cancer, especially when taken over long periods. The findings? While not all risks are definitive, some commonly used drugs are raising red flags.
What the Science Says About Medication-Linked Prostate Cancer
Certain drugs may influence hormonal balance, prostate cell growth, or DNA repair mechanisms—factors that can potentially increase cancer risk over time. Men on long-term medication regimens are being urged to discuss their risks with a doctor.
Remember: not every medication poses a serious risk—but knowledge is power, especially when it comes to prevention.
List of Medications Linked to Prostate Cancer Risk
🟥 Testosterone Replacement Therapy (TRT)
While helpful for some, TRT may stimulate prostate cell growth, potentially accelerating undetected tumors in men with pre-existing conditions.
🟨 5-Alpha Reductase Inhibitors (e.g., Finasteride, Dutasteride)
Commonly prescribed for enlarged prostate (BPH). Some studies suggest a reduced overall risk, but a higher risk of aggressive cancers in certain men.
🟦 Certain Antihypertensives (e.g., Thiazide Diuretics)
Long-term use has been correlated with increased prostate volume, although evidence remains mixed.
🟩 Immunosuppressants
Used after organ transplants or to manage autoimmune disease. May impair the body’s cancer-fighting defenses.
🟫 Anti-Inflammatories (Long-Term NSAID Use)
While short-term use may help, chronic overuse has been linked to changes in prostate tissue in some studies.
What Should You Do If You’re on One of These Medications?
Don’t stop taking your medications without speaking to your doctor.
Ask about prostate screening if you’re on long-term hormonal or cardiac medications.
Consider alternative therapies where the benefit-risk balance is more favorable.
View the full medication list and consult your provider about your risk. Early awareness could be life-saving.